Food Supplements Hazard Characterization

Format	Author(s)	Title / Description	Date added	Details
	Haller, Christine A., and Neal L. Benowitz	Adverse Cardiovascular and Central Nervous System Events Associated with Dietary Supplements Containing Ephedra Alkaloids Abstract of a report on a study in which causation was assessed for 140 adverse event reports related to ephedra alkaloids. The abstract summarizes the background, methods, results, and conclusions, and the full text is available with a subscription. The page also gives a list of other articles that have cited this article. (more) Publication Date: Thursday, December 21, 2000	Dec 9, 2002
	Elliott, Victoria Stagg	Code Green: Seeing the Side Effects of Alternative Supplements This report discusses side effects of herbal supplements as well as labeling and diagnosis issues. It also includes, under "Additional information," the reasons for taking, adverse reactions, and other drug conflictions of ephedra/ma huang, St. John's Wort, kava kava, yohimbine, and ginkgo biloba. (more) Publication Date: Monday, March 5, 2001	Aug 15, 2002
	Center for Food Safety and Applied Nutrition, Food and Drug Administration	Consumer Advice Gives answers to consumers for common questions regarding foodborne illness, food preparation, food away from home, food storage, seafood, produce and fruit juice, dietary supplements, cosmetics, nutrition and weight loss, food labeling, and more. (more)	May 29, 2002
	Food and Drug Administration	Dietary Supplements Containing Ephedrine Alkaloids Final Rule Summary This page provides summary information regarding FDA's evaluation of and final rule regarding ephedrine alkaloids.	Feb 9, 2004
	Sanders, LesLee F.	Ephedra This document provides an overview of ephedra, including uses, common dosage, side effects, food drug interactions, and the safety of using this product. (more)	Jul 30, 2002
	Shekelle, Paul, et al./Southern California Evidence-Based Practice Center, RAND	Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement: Clinical Efficacy and Side Effects This report includes a literature review and meta-analysis of data and research related to the efficacy and safety of ephedra and ephedrine used for weight loss or for enhancing athletic performance. (more) Publication Month: February 2003	Feb 9, 2004
	Dybing, E., et al.	Hazard Characterisation of Chemicals in Food and Diet: Dose Response, Mechanisms and Extrapolation Issues This report discusses biologically-based hazard characterization. It addresses the main issues in hazard characterization, and it focuses on low molecular weight chemicals. Topics covered include modes of toxicological action, causes of underlying variability in toxic responses, dose-response considerations, species differences and interspecies extrapolation, and more. Purchase or subscription is required to access full text. (more) Publication Month: February 2002	Jul 23, 2002
	Department of Health Promotion and Wellness, Center for Health Promotion and Preventive Medicine, U.S. Army	Herb and Drug Interactions This document gives drug interactions and side effects for gingko biloba, ginseng, feverfew, garlic, devil's claw, dong quai, papaya, and ginger, ephedra/ma huang, kava, echinacea, St. John's wort, capsaicin/chili pepper, licorice, and valerain. (more)	Jul 30, 2002
	Department of Health Promotion and Wellness, Center for Health Promotion and Preventive Medicine, U.S. Army	Herb and Supplement Information Sheet This table gives definition, claims, research, mechanism of action, and side effects, dosing, and other information for a long list of herbal supplements. (more)	Jul 30, 2002
	Hennessy, Lori	Nutritional Supplements: Pushing the Limits This presentation outlines the dangers of nutritional supplements. It includes a list of FDA's dangerous herbs and their side effects and discusses ephedra, St. John's wort, gingko biloba, ginseng, echinacea, DHEA, glucosamine, chondroitin, chromium, amino acids, creatine, and androstenedione. (more)	Jul 30, 2002
	Cantox Health Sciences International	Safety Assessment and Determination of a Tolerable Upper Limit for Ephedra Assessment of safety and establishment of a safe upper intake level for ephedra/ephedrine alkaloids. Appendices include "Analysis of the Available Adverse Event Reports (AERs) for Ephedra," "Review of Published Case Reports," and "Boozer et al., (2000) Abstract and Analysis". (more) Publication Date: Tuesday, December 19, 2000	Sep 16, 2004
	United Kingdom Scientific Advisory Committee on Nutrition	Scientific Advisory Committee on Nutrition: Review of Dietary Advice on Vitamin A Draft of review of dietary advice on vitamin A. Comments are invited. There are eight annexes, including: "Current Legislation regarding food supplements and food fortification", "Tolerable Upper Intake Levels of preformed Vitamin A", "Human studies of retinol intake and bone health", "Comparison of diets in UK, US, and Sweden", "Adjustment of NDNS estimates of retinol intake using data from EPIC-Oxford", and "Percentage of consumers whose intakes fall above/below Guidance Level and LRNI under different scenarios". (more) Deadline: Friday, April 8, 2005 Publication Month: December 2004	Jan 11, 2005
	Food and Agricultural Organization of the United Nations/World Health Organization	Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee on Food Additives (JECFA 1956-2001) (First through fifty-seventh meetings): Internet Edition Searchable collection of summaries of evaluations performed on the safety of additives, contaminants, and veterinary drug residues. (more) Publication Year: 2001	Aug 31, 2001

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