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Scrapie

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ID Author(s) Title / Description Publication Date
5580 Health and Consumer Protection Directorate-General, European Commission Case of BSE in a Goat Confirmed: Commission Extends Testing Programme
URL: http://europa.eu.int/rapid/pressReleasesAction.do?reference=IP/05/105&format=HTML&aged=0&language=EN&guiLanguage=EN
Format: HTML PDF
Recent data confirm that a goat slaughtered in France in 2002 had BSE. This report provides an overview of the findings and the ongoing testing regime in Europe. The…
Recent data confirm that a goat slaughtered in France in 2002 had BSE. This report provides an overview of the findings and the ongoing testing regime in Europe. The document is available in other formats and languages. Included are links to the scientific report and Questions & Answers on TSE in goats
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Source: Health and Consumer Protection Directorate-General, European Commission

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20050128Jan 28, 2005
5046 World Organization for Animal Health (OIE) Manual of Diagnostic Tests and Vaccines for Terrestrial Animals
URL: http://www.oie.int/eng/normes/en_mmanual.htm
Format: HTML
This manual discusses laboratory diagnostic tests and information on vaccines for certain animal diseases.
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Source: World Organization for Animal Health

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200400002004
4123 Gale, P. Risk Assessment: Use of Composting and Biogas Treatment to Dispose of Catering Waste Containing Meat
URL: http://www.defra.gov.uk/foodfarm/byproducts/documents/report5.pdf
Format: PDF
Assessment of risks to humans and livestock from pathogens in compost associated with uncooked meat in catering (including household) waste. Pathogens considered include BSE, scrapie, foot and mouth disease…
Assessment of risks to humans and livestock from pathogens in compost associated with uncooked meat in catering (including household) waste. Pathogens considered include BSE, scrapie, foot and mouth disease virus, classical swine fever virus, swine vesicular disease, African swine fever, Newcastle disease, Cryptosporidium, Toxoplasma gondii, Salmonella, E. coli O157:H7, Campylobacter, Trichinella spiralis, Clostridium botulinum, and plant pathogens. Includes an appendix entitled "Response to the Survey of Meat Preparation in Kitchens"
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Source: United Kingdom Department for Environment, Food and Rural Affairs

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20020500May 2002
5112 Health and Consumer Protection Directorate-General, European Commission TSE in Goats
URL: http://ec.europa.eu/food/food/biosafety/bse/goats_index_en.htm
Format: HTML
This page links to information, press releases, fact sheets, surveillance data, and scientific opinions regarding TSE in goats
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Source: Health and Consumer Protection Directorate-General, European Commission

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General TSEs

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ID Author(s) Title / Description Publication Date
8962 European Commission Recently Added The TSE Road map 2: A Strategy paper on Transmissible Spongiform Encephalopathies for 2010-2015
URL: http://ec.europa.eu/food/food/biosafety/tse_bse/docs/roadmap_en.pdf
Format: PDF
The aim of this Communication is to outline future possible amendments allowing a review of the measures to align them with the situation where the EU is finally on…

The aim of this Communication is to outline future possible amendments allowing a review of the measures to align them with the situation where the EU is finally on the last pathway to eradicate BSE within its cattle population.

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Source: European Commission

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20100700Jul 2010
8742 European Food Safety Authority Journal Scientific Opinion on Analytical sensitivity of approved Transmissible Spongiform Encephalopathy (TSE) rapid tests – new data for assessment of two rapid tests
URL: http://www.efsa.europa.eu/en/efsajournal/scdoc/1591.htm
Format: HTML PDF
This Opinion provides a scientific assessment of a new study (“re-assessment study”) performed to re-assess the analytical sensitivity of the two above rapid tests with cattle BSE samples.
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Source: European Food Safety Authority Journal, Vol. 8, No.4, 2010 p. 1591-1601.

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20100400Apr 2010
8578 Mathews, J. Review of Scientific Evidence to Inform Australian Policy on Transmissible Spongiform Encephalopathies (TSEs)--2009 Addendum
URL: http://www.health.gov.au/internet/main/publishing.nsf/Content/B081C7E60E542608CA257654000AF13E/$File/tse-report-oct-09.pdf
Format: HTML
This 2009 Addendum emphasises those questions that could not be resolved in earlier reports because of limited information. Otherwise, it is intended to be as selfcontained as possible. The…
This 2009 Addendum emphasises those questions that could not be resolved in earlier reports because of limited information. Otherwise, it is intended to be as selfcontained as possible. The Executive Summary with Conclusions is supported by a short Scientific Review, and by risk estimates and essential references dealing with evidence that may have changed since the earlier reviews. It has been impossible to access all potentially relevant references in the time available. The earlier reports providing scientific advice to government on TSE policy are available as annexes.
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Source: Department of Health and Ageing, Therapeutic Goods Administration (TGA), Food Standards Australia and New Zealand (FSANZ), and the Department of Agriculture, Forestry and Fisheries (DAFF), Commonwealth of Australia

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20091000Oct 2009
7331 International Forum for Transmissible Animal Diseases and Food Safety TAFS Position Paper on the Safety of Bovine Milk and Bovine Milk Products
URL: http://tafsforum.org/position_papers/TAFS_POSITION_PAPER_MILK_2009_FEB.pdf
Format: PDF
This paper reviews scientific evidence and studies related to the transmission of BSE and TSEs to humans through bovine milk.
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Source: International Forum for Transmissible Animal Diseases and Food Safety

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20090200Feb 2009
8452 European Food Safety Authority Scientific Opinion on Analytical sensitivity of approved TSE rapid tests
URL: http://www.efsa.europa.eu/en/scdocs/doc/s1436.pdf
Format: PDF
The current scientific opinion gives an overview of the methodology and results of the Community Reference Laboratory (CRL) study. The CRL study investigated the analytical sensitivity of all the…
The current scientific opinion gives an overview of the methodology and results of the Community Reference Laboratory (CRL) study. The CRL study investigated the analytical sensitivity of all the approved TSE rapid tests and also investigated the stability of Atypical scrapie positive samples when stored frozen at -80°C. The Panel on Biological Hazards (BIOHAZ Panel) acknowledges that for the first time all the tests were evaluated against the same sample set, allowing a direct comparison of their analytical sensitivity and concludes that the study findings provide valuable information in determining the continued suitability of tests currently used for TSE monitoring in the EU.
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Source: European Food Safety Autority Journal, Vol. 7, No. 12, 2009, p. 1436.

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200900002009
7385 Panel on Biological Hazards, European Food Safety Authority Certain Aspects related to the Feeding of Animal Proteins to Farm Animals - Scientific Opinion of the Panel on Biological Hazards
URL: http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1178659674335.htm
Format: HTML
Opinion adopted Oct 17, 2007 resulting from an evaluation of risk from using non-ruminant MBM in pig and poultry feed, once it is possible to distinguish protein origin up…
Opinion adopted Oct 17, 2007 resulting from an evaluation of risk from using non-ruminant MBM in pig and poultry feed, once it is possible to distinguish protein origin up to different species and the introduction of certain tolerance levels with regard to small quantities of MBM in animal feed and the parameters which could be utilized to define these tolerance levels and quantities.
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Source: European Food Safety Autority Journal, Vol. 576, 2007, P. 1-41./Panel on Biological Hazards, European Food Safety Authority

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20071115Nov 15, 2007
7507 Panel on Biological Hazards, European Food Safety Authority Scientific Opinion of the Panel on Biological Hazards: Protocol for a Preliminary Evaluation of Ante-mortem TSE Tests for Ruminants
URL: http://www.efsa.europa.eu/EFSA/Scientific_Opinion/biohaz_op_ej540_live_animal_%20test_en.pdf
Format: HTML PDF
Opinion adopted September 7th, 2007 resulting from the evaluation of ante-mortem tests to detect TSE in ruminants. It outlines a general proof of principle and provides preliminary guidance to…
Opinion adopted September 7th, 2007 resulting from the evaluation of ante-mortem tests to detect TSE in ruminants. It outlines a general proof of principle and provides preliminary guidance to test developers on necessary investigations that should precede any formal evaluation.
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Source: European Food Safety Autority Journal, Vol. 540, 2007, P. 1-12./Panel on Biological Hazards, European Food Safety Authority

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20071002Oct 2, 2007
7270 Scientific Panel on Biological Hazards, European Food Safety Authority Opinion of the Scientific Panel BIOHAZ on the CRL report on batch testing of TSE rapid tests: sample selection and test sensitivity issues
URL: http://www.efsa.europa.eu/en/science/biohaz/biohaz_opinions/ej445_batch.html
Format: HTML PDF
Opinion adopted March 7, 2007 resulting from evaluation of a report of the Community Reference Laboratory (CRL) on batch testing of Transmissible Spongiform Encephalopathy (TSE) rapid test kits which…
Opinion adopted March 7, 2007 resulting from evaluation of a report of the Community Reference Laboratory (CRL) on batch testing of Transmissible Spongiform Encephalopathy (TSE) rapid test kits which highlighted some matters of concern including sample selection and test sensitivity issues.
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Source: European Food Safety Autority Journal, Vol. 443, 2007, p. 1-18./Panel on Biological Hazards, European Food Safety Authority

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20070323Mar 23, 2007
7269 Scientific Panel on Biological Hazards, European Food Safety Authority Opinion of the Scientific Panel BIOHAZ on certain aspects related to the risk of Transmissible Spongiform Encephalopathies (TSEs) in ovine and caprine animals
URL: http://www.efsa.europa.eu/en/science/biohaz/biohaz_opinions/ej466_tse_ovicap.html
Format: HTML PDF
Opinion adopted on March 8, 2006 concerning that if there is any evidence for an epidemiological or molecular link between classical and/or atypical scrapie and Transmissible Spongiform Encephalopathies (TSEs)…
Opinion adopted on March 8, 2006 concerning that if there is any evidence for an epidemiological or molecular link between classical and/or atypical scrapie and Transmissible Spongiform Encephalopathies (TSEs) in humans.
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Source: European Food Safety Autority Journal, Vol. 466, 2007, p. 1-10./Panel on Biological Hazards, European Food Safety Authority

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20070321Mar 21, 2007
6179 European Commission The TSE Roadmap
URL: http://europa.eu.int/comm/food/food/biosafety/bse/roadmap_en.pdf
Format: PDF
Paper on the European Commission's BSE strategy for the short, medium, and long-term. Annexes include "Monitoring data," "Costs linked to the surveillance programme," and more
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Source: Health and Consumer Protection Directorate-General, European Commission

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20050715Jul 15, 2005
5580 Health and Consumer Protection Directorate-General, European Commission Case of BSE in a Goat Confirmed: Commission Extends Testing Programme
URL: http://europa.eu.int/rapid/pressReleasesAction.do?reference=IP/05/105&format=HTML&aged=0&language=EN&guiLanguage=EN
Format: HTML PDF
Recent data confirm that a goat slaughtered in France in 2002 had BSE. This report provides an overview of the findings and the ongoing testing regime in Europe. The…
Recent data confirm that a goat slaughtered in France in 2002 had BSE. This report provides an overview of the findings and the ongoing testing regime in Europe. The document is available in other formats and languages. Included are links to the scientific report and Questions & Answers on TSE in goats
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Source: Health and Consumer Protection Directorate-General, European Commission

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20050128Jan 28, 2005
1356 Institute of Food Science and Technology (IFST) Bovine Spongiform Encephalopathy (BSE) and Variant Creutzfeldt-Jakob Disease (vCJD) in Humans
URL: http://www.ifst.org/science_technology_resources/for_food_professionals/information_statements/19499/Bovine_Spongiform_Encephalopathy_%28BSE%29_and_Variant_Creutzfeldt-Jakob_Disease_%28vCJD%29
Format: HTML
This information statement highlights available data and research on BSE and vCJD up to September 2004. Includes discussion of origin and spread, the infective agent, infectivity of bovine materials,…
This information statement highlights available data and research on BSE and vCJD up to September 2004. Includes discussion of origin and spread, the infective agent, infectivity of bovine materials, health controls, BSE risk by country or region, vertical transmission, BASE, BSE and sheep, vCJD, detection methods, therapeutic agents, research needs, and more
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Source: Institute of Food Science and Technology

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20041000Oct 2004
4434 European Food Safety Authority Opinion of the European Food Safety Authority on a Surveillance Programme for Chronic Wasting Disease in the European Union. (Question No EFSA-Q-2003-088)
URL: http://www.seac.gov.uk/papers/efsa-annex%205.pdf
Format: HTML PDF
Opinion adopted June 3, 2004 regarding a surveillance program for chronic wasting disease and other TSEs in cervids in the European Union
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Source: European Food Safety Autority Journal, Vol. 70, 2004, p. 1-7./Panel on Biological Hazards, European Food Safety Authority

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20040708Jul 8, 2004
4408 Unit D2 - Biological Risks, Directorate D - Food Safety: Production and Distribution Chain, Health and Consumer Protection Directorate-General, European Commission Effectively Enforced Feed-Ban
URL: http://europa.eu.int/comm/food/food/biosafety/bse/bse_51_en.pdf
Format: PDF
Guidance document regarding indicators to give proof of an effectively enforced ban of feeding ruminants with protein derived from mammals. Includes a list of Community legislation related to the…
Guidance document regarding indicators to give proof of an effectively enforced ban of feeding ruminants with protein derived from mammals. Includes a list of Community legislation related to the feed ban
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Source: Health and Consumer Protection Directorate-General, European Commission

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20040400Apr 2004
3785 Larson, J. Bovine Spongiform Encephalopathy (BSE) and Other Animal Related Transmissible Spongiform Encephalopathies
URL: http://www.nal.usda.gov/awic/pubs/bsebib.htm
Format: HTML
Bibliography of resources on BSE and other TSEs, including descriptors and abstracts for many articles
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Source: Animal Welfare Information Center, National Agricultural Library, Agricultural Research Service, U.S. Department of Agriculture

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20040100Jan 2004
3355 European Commission Commission Regulation (EC) No 1915/2003 of 30 October 2003 Amending Annexes VII, VIII and IX to Regulation (EC) No 999/2001 of the European Parliament and of the Council as Regards the Trade and Import of Ovine and Caprine Animals and the Measures . . .
URL: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2003:283:0029:0033:EN:PDF
Format: HTML PDF
Regulation that amends EC Regulation 999/2001 with regards to measures to be taken after the confirmation of TSEs in bovine, ovine, or caprine animals and with regards to the…
Regulation that amends EC Regulation 999/2001 with regards to measures to be taken after the confirmation of TSEs in bovine, ovine, or caprine animals and with regards to the import of ovine and caprine animals
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Source: Official Journal of the European Union, L 283, Oct. 31, 2003, p. 29-33./Eur-Lex, European Union

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20031031Oct 31, 2003
3172 Center for Veterinary Medicine, Food and Drug Administration (FDA) Guidance for Industry: Use of Material from Deer and Elk in Animal Feed
URL: http://www.fda.gov/OHRMS/DOCKETS/98fr/03d-0186-gdl0001.DOC
Format: MS Word
Guidance document regarding the use of material in animal feed from deer and elk that are positive for or considered at high risk for Chronic Wasting Disease
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Source: Division of Dockets Management, Food and Drug Administration

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20030915Sep 15, 2003
3049 European Commission Questions and Answers on TSE in Sheep and Goats
URL: http://europa.eu.int/rapid/start/cgi/guesten.ksh?p_action.gettxt=gt&doc=MEMO/03/157|0|RAPID&lg=EN&display=
Format: HTML
This fact sheet includes general information about TSE, sheep, and goats in the EU, information on research in this area, and information about EU legislation and measures regarding TSEs…
This fact sheet includes general information about TSE, sheep, and goats in the EU, information on research in this area, and information about EU legislation and measures regarding TSEs in sheep and goats. Links to relevant documents are provided
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Source: European Commission

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20030724Jul 24, 2003
2085 Media Centre, Communications Office of the Director-General's Office, World Health Organization (WHO) Variant Creutzfeldt-Jakob Disease
URL: http://www.who.int/mediacentre/factsheets/fs180/en/
Format: HTML
Fact sheet on vCJD. It addresses the number of cases, epidemiology, clinical features and diagnosis, probable cause, association with BSE, other TSEs, preventive measures, and WHO involvement and recommendations
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Source: Media Centre, Communications Office of the Director-General's Office, World Health Organization

Keywords:
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20021100Nov 2002
1211 Scientific Steering Committee, Health and Consumer Protection Directorate-General, European Commission Safety of Animal Rennet in Regard to Risks from Animal TSE and BSE in Particular
URL: http://europa.eu.int/comm/food/fs/sc/ssc/out265_en.pdf
Format: PDF
This opinion paper and supporting report discuss the safety of rennet obtained from calves, cattle, small ruminants, and pigs with respect to TSE and BSE
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Source: European Commission

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20020516May 16, 2002
3809 Center for Food Safety and Applied Nutrition (CFSAN), Food and Drug Administration (FDA)/RTI Animal-Derived Cosmetic Ingredient Database
URL: http://foodrisk.org/exclusives/ADCID/
Format: HTML
RTI, under contract with FDA, constructed this database on cosmetic ingredients that could potentially be derived from animals. These ingredients are of interest because of the potential for transmission…
RTI, under contract with FDA, constructed this database on cosmetic ingredients that could potentially be derived from animals. These ingredients are of interest because of the potential for transmission of Bovine Spongiform Encephalopathy (BSE) or other Transmissible Spongiform Encephalopathies (TSEs)
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Source: FoodRisk.org

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20020400Apr 2002
1214 Scientific Steering Committee, Health and Consumer Protection Directorate-General, European Commission Opinion on TSE Infectivity Distribution in Ruminant Tissue (State of Knowledge, December 2001)
URL: http://europa.eu.int/comm/food/fs/sc/ssc/out241_en.pdf
Format: PDF
This document includes tissue infectivity tables related to BSE in cattle, discussion of the head of cattle, sheep and goats as potential specified risk material, infectivity tables related to…
This document includes tissue infectivity tables related to BSE in cattle, discussion of the head of cattle, sheep and goats as potential specified risk material, infectivity tables related to scrapie in sheep and goats, and a detailed supporting report
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Source: European Commission

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20020110Jan 10, 2002
1215 Scientific Steering Committee, Health and Consumer Protection Directorate-General, European Commission Opinion on Requirements for Statistically Authoritative BSE/TSE Surveys
URL: http://ec.europa.eu/food/fs/sc/ssc/out238_en.pdf
Format: PDF
This opinion and supporting report discuss the requirements for statistical surveys to be used for classifying the BSE status of a country
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Source: European Commission

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20011130Nov 30, 2001
115 Center for Food Safety and Applied Nutrition (CFSAN), Food and Drug Administration (FDA) [ARCHIVE] " href="http://web.archive.org/web/20080609010803/http://vm.cfsan.fda.gov/~mow/intro.html" title="http://web.archive.org/web/20080609010803/http://vm.cfsan.fda.gov/~mow/intro.html" name="link-115" class="title">Foodborne Pathogenic Microorganisms and Natural Toxins Handbook: The "Bad Bug Book"
URL: http://web.archive.org/web/20080609010803/http://vm.cfsan.fda.gov/~mow/intro.html
Format: HTML
Handbook with information on foodborne pathogenic microorganisms and natural toxins, including information on the associated disease, associated foods, target populations, outbreaks, and more. Appendices include "Infective dose," "Epidemiology summary…

Handbook with information on foodborne pathogenic microorganisms and natural toxins, including information on the associated disease, associated foods, target populations, outbreaks, and more. Appendices include "Infective dose," "Epidemiology summary table," "Factors affecting microbial growth in foods," "Foodborne Disease Outbreaks, United States 1988-1992," and "Additional Foodborne Disease Outbreak Articles and Databases"

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Source: Center for Food Safety and Applied Nutrition, Food and Drug Administration

Keywords:
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19920100Jan 1992
6151 Health and Consumer Protection Directorate-General, European Commission BSE - Annual Reports
URL: http://europa.eu.int/comm/food/food/biosafety/bse/annual_reps_en.htm
Format: HTML
Annual reports regarding the monitoring and testing of ruminants for TSE in EU Member States
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Source: Health and Consumer Protection Directorate-General, European Commission

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2346 United Kingdom Department for Environment Food and Rural Affairs DEFRA BSE: Statistics
URL: http://www.defra.gov.uk/foodfarm/farmanimal/diseases/atoz/bse/statistics/index.htm
Format: HTML
This site provides statistics for BSE and other TSEs, mostly in Great Britain
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Source: United Kingdom Department for Environment Food and Rural Affairs

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2750 International Forum for TSE and Food Safety International Forum for TSE and Food Safety: TAFS
URL: http://www.tafsforum.org
Format: HTML
Non-profit organization that works for the communication of information related to TSEs and food safety. The website includes activities, papers, and more
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Source: International Forum for TSE and Food Safety

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5253 Spongiform Encephalopathy Advisory Committee List of References: List of Scientific Papers Supplied to SEAC Members by the Secretariat
URL: http://www.seac.gov.uk/papers/references.htm
Format: HTML
Lists of references related to TSEs
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Source: Spongiform Encephalopathy Advisory Committee

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7788 European Food Safety Authority Opinion of the Scientific Panel on Biological Hazards on a request from the European Commission on the human and animal exposure risk related to Transmissible Spongiform Encephalopathies (TSEs) from milk and milk products derived from small ruminants.
URL: http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1211902166533.htm
Format: HTML PDF
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Source: The European Food Safety Autority Journal, v.849, p. 1-37.

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8543 Food and Drug Administration Risk Assessment/Safety Assessment
URL: http://www.fda.gov/Food/ScienceResearch/ResearchAreas/RiskAssessmentSafetyAssessment/default.htm
Format: HTML
This page provides various resources for risk assessment and safety assessment information through the U.S. Food and Drug Administration. Topic areas include; basic information, allergens, specific bacteria, food additives,…
This page provides various resources for risk assessment and safety assessment information through the U.S. Food and Drug Administration. Topic areas include; basic information, allergens, specific bacteria, food additives, food defense, and chemical hazards.
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Source: Food and Drug Administration

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5252 Spongiform Encephalopathy Advisory Committee Spongiform Encephalopathy Advisory Committee: SEAC
URL: http://www.seac.gov.uk/
Format: HTML

UK advisory committee on TSEs that is sponsored by DEFRA, the Department of Health, and the FSA. The website includes information on their meetings, publications, and more

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Source: Spongiform Encephalopathy Advisory Committee

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41 Department of Computer Science, University of Maryland Transmissible Spongiform Encephalopathy (TSE) Risk Project
URL: http://www.cs.umd.edu/projects/fsrac/
Format: HTML
Demonstration of SHOE web-page annotation using TSE transmission as an example
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Source: Department of Computer Science, University of Maryland

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39 Mark W. TSE Risk Path Analyzer
URL: http://www.cs.umd.edu/projects/fsrac/tsepaths.html
Format: HTML
Tool for examining potential exposure pathways of transmissable spongiform encephalopathies
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Source: Joint Institute of Food Safety and Applied Nutrition

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