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General Chemical Hazards Exposure Assessment

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ID Author(s) Title / Description Publication Date
7712 Panel on Plant protection products and their Residues, European Food Safety Authority Opinion of the Scientific Panel on Plant Protection Products and their Residues to Evaluate the Suitability of Existing Methodologies and, if Appropriate, the Identification of New Approaches to Assess Cumulative and Synergistic Risks from Pesticides to Human Health with a View to Set MRLs for those Pesticides in the Frame of Regulation (EC) 396/2005
URL: http://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1178712607885.htm
Format: HTML PDF
Opinion adopted on April 15, 2008 resulting from evaluating and possibly refining existing methodologies for assessing risks of exposure to two or more pesticides in combination, particularly in the context of setting MRLs according to Regulation (EC) 396/2005.
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Source: European Food Safety Autority Journal, Vol.704, 2008, p. 1-84./Panel on Plant protection products and their Residues, European Food Safety Authority

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20080530May 30, 2008
7518 Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) Animal Feed Impact on Food Safety
URL: http://www.fao.org/ag/againfo/resources/en/publications/agapubs/A1507E_Animal-Feed.pdf
Format: PDF
Report of a Joint FAO/WHO Expert Meeting on Animal Feed Impact on Food Safety which was held at FAO Headquarters in Rome from 8 to 12 October 2007. The meeting concluded that ensuring safe feed is an important component of efforts to reduce and prevent food safety hazards and indicated several potential measures to ensure safe feed. Agenda of the meeting, list of participants, experts' resumes and list of documents are included as appendices. The report is being translated in French and Spanish. Printed copies may be requested from: Daniela.Battaglia@fao.org.
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Source: Food and Agriculture Organization of the United Nations

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200800002008
7907 Environmental Protection Agency (EPA) Microbial Risk Assessment Thesaurus
URL: http://www.epa.gov/waterscience/criteria/humanhealth/microbial/thesaurus/
Format: HTML PDF
Federal and international agencies, private sector organizations, and academics use terms and definitions differently in their microbial risk assessments. This Thesaurus is a compendium of risk assessment terms found in frameworks, methodologies, and assessments. It provides insight into how various entities use specific microbial risk assessment terms in their activities and helps those responsible for such assessments both conduct and communicate about them more effectively. This Thesaurus was developed by the USEPA, Office of Water.
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Source: Environmental Protection Agency

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20070900Sep 2007
6778 North American Commission for Environmental Cooperation Children's Health and the Environment in North America: A First Report on Available Indicators and Measures
URL: http://www.cec.org/programs_projects/pollutants_health/children/index.cfm?varlan=english
Format: HTML PDF
Report on indicators from Canada, the U.S., and Mexico related to children's environmental health. Topics covered include pesticide residues, waterborne diseases, and more. Appendices include "Overview of Recommended Indicators from the CEC Council," "153 Matched Chemicals," and more. Individual country reports are also available.
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Source: North American Commission for Environmental Cooperation

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200600002006
6834 Risk Assessment Forum, Environmental Protection Agency (EPA) Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants
URL: http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=146583
Format: HTML PDF
Guidance document that provides a set of age groupings of children to consider in exposure and risk assessments. Includes discussion of how to apply the age groupings in exposure and risk assessment. There is an appendix entitled "Preliminary Reevaluation of Exposure Factors Data for Children." The peer review document, draft report, EPA responses to comments, and related workshop report are also available from this page.
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Source: National Center for Environmental Assessment, Office of Research and Development, Environmental Protection Agency

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20051100Nov 2005
6271 National Center for Environmental Assessment, Office of Research and Development, Environmental Protection Agency (EPA) Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment (External Review Draft 2005)
URL: http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=135427
Format: HTML PDF
Draft report on the evaluation and use of PBPK models in human health risk assessment. Appendices include "Algorithms for predicting chemical-specific parameters for PBPK models," "List of publications relevant to PBPK modeling of environmental chemicals and its use," and "Partition coefficients and metabolic rate constants for PBPK modeling of environmental." Comments are requested. The public comment period has been extended in 70 FR 48950.
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Source: National Center for Environmental Assessment, Office of Research and Development, Environmental Protection Agency

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20050600Jun 2005
5774 International Workshop on Total Diet Studies (3rd : 2004 : Paris, France) GEMS/Food Total Diet Studies: Report of the 3rd International Workshop on Total Diet Studies, Paris, France, 14-21 May 2004
URL: http://www.who.int/foodsafety/publications/chem/en/TDS_Paris_en.pdf
Format: PDF
Report of this workshop on total diet studies. Annexes include "Summary of Selected Presentations," "Recommendations of the 2nd International Total Diet Study Workshop, Brisbane, Australia, 4-15 February, 2002," and more.
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Source: Food Safety Department, World Health Organization

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200500002005
6001 GEMS/Food, Food Safety Department, World Health Organization (WHO) Total Diet Studies: a Recipe for Safer Food
URL: http://www.who.int/foodsafety/publications/chem/recipe/en/index.html
Format: HTML PDF
Brochure on total diet studies, including what they are, why to do them, costs and benefits, examples of priority contaminants, and more.
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Source: Food Safety Department, World Health Organization

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200500002005
5453 Exposure Modelling Subcommittee, IPCS Harmonization Project Exposure Assessment Working Group, International Programme on Chemical Safety Principles of Characterizing and Applying Human Exposure Models
URL: http://www.who.int/ipcs/methods/harmonization/exposure_models/en/
Format: HTML PDF
Draft report for comment on exposure modeling for environmental pollutants and food additives.
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Source: International Programme on Chemical Safety

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20041100Nov 2004
4886 National Center for Environmental Assessment, Office of Research and Development, Environmental Protection Agency (EPA) Example Exposure Scenarios
URL: http://cfpub2.epa.gov/ncea/cfm/recordisplay.cfm?deid=85843
Format: HTML PDF
This document presents exposure scenarios for different exposure pathways and demonstrates the application of data from the Exposure Factors Handbook in estimating exposures. For each scenario, an exposure algorithm, exposure factor inputs, calculations, and exposure characterization and uncertainties are presented. Ingestion pathways described include contaminated homegrown vegetables, homegrown tomatoes, beef, dairy products, drinking water, fish, and breastmilk.
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Source: National Center for Environmental Assessment, Office of Research and Development, Environmental Protection Agency

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20040400Apr 2004
5338 Exponent, Inc. Calendex™
URL: http://www.exponent.com/calendex_software/
Format: HTML
Aggregate exposure modeling tool for chemical hazards.
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Source: Exponent, Inc.

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1694 Office of Pollution Prevention and Toxics, Environmental Protection Agency (EPA) Chemicals in the Environment: OPPT Chemical Fact Sheets
URL: http://www.epa.gov/docs/chemfact/
Format: HTML PDF Text
These fact sheets for selected environmental chemicals describe exposure routes, production and consumption of products, effects of exposure (including dose-response information, toxicity, and carcinogenicity), regulation information, contact information, and more.
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Source: Office of Pollution Prevention and Toxics, Environmental Protection Agency

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2850 Microbiological and Chemical Exposure Assessment Research Division, National Exposure Research Laboratory, Office of Research and Development, Environmental Protection Agency (EPA) Dietary Exposure Potential Model
URL: http://www.epa.gov/nerlcwww/depm.htm
Format: HTML
Model and database system for estimating dietary exposure to chemical residues. Data is included from government-sponsored national food intake surveys and chemical residue monitoring programs. The user can add additional foods or chemicals and associated data, and the user can import food diaries for exposure analysis. There is also an option to include exposure from tap water.
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Source: Microbiological and Chemical Exposure Assessment Research Division, National Exposure Research Laboratory, Office of Research and Development, Environmental Protection Agency

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966 Division of Data Services, National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention (CDC) Healthy People . . . tracking the Nation's health
URL: http://www.cdc.gov/nchs/healthy_people.htm
Format: HTML Windows Software
This page provides data, documentation, and publications from Healthy People 2010 and Healthy People 2000. Focus groups for Healthy People 2010 include Food Safety, Cancer, Environmental Health, Health Communication, Nutrition, and more. To access data for Healthy People 2010, follow the link for DATA2010; you may log on to CDC WONDER as an anonymous user.
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Source: Division of Data Services, National Center for Health Statistics, Centers for Disease Control and Prevention

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6067 National Food Centre, Teagasc National Food Residue Database: NFRD
URL: http://nfrd.teagasc.ie/
Format: HTML
Database of data on veterinary drugs, prohibited substances, pesticides, heavy metals, dioxins and PCBs, mycotoxins, and other contaminants from Irish monitoring and surveillance programs or studies and surveys.
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Source: National Food Centre, Teagasc

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3208 New Zealand Food Safety Authority New Zealand Total Diet Survey
URL: http://www.nzfsa.govt.nz/science-technology/research-projects/total-diet-survey/index.htm
Format: HTML
This page provides information about the 2003-04 New Zealand Total Diet Survey, in which foods are analyzed in the form they are consumed in order to estimate exposure to chemical residues, contaminants, and nutrients. Links are provided to the report from the 1997/98 New Zealand Total Diet Survey as well as to similar studies conducted by other countries.
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Source: New Zealand Food Safety Authority

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7796 Food and Agriculture Organization of the United Nations (FAO) (FAO) / World Health Organization (WHO) (WHO) PRINCIPLES AND METHODS FOR 1 THE RISK ASSESSMENT OF CHEMICALS IN FOOD: Chapter 6 DIETARY EXPOSURE ASSESSMENT OF CHEMICALS IN FOOD
URL: http://www.who.int/ipcs/food/dietary_exposure.pdf
Format: PDF

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Source: World Health Organization (WHO)

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1435 National Toxicology Program, Public Health Service, U.S. Department of Health and Human Services (DHHS) Report on Carcinogens
URL: http://ntp.niehs.nih.gov/index.cfm?objectid=72016262-BDB7-CEBA-FA60E922B18C2540
Format: HTML PDF
Report on substances that are or may be human carcinogens. It includes carcinogenicity, exposure, and regulations by Federal agencies to limit exposures. It also includes a list of names and synonyms of known carcinogens and substances reasonably anticipated to be carcinogens, information on manufacturing processes, occupations, and exposure circumstances known to be carcinogens, a listing of substances removed from the report, and a listing of substances reviewed but not recommeded for listing in the report.
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Source: National Toxicology Program, Public Health Service, U.S. Department of Health and Human Services

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1623 Risk Assessment Program, Toxicology and Risk Analysis Section, Life Sciences Division, Oak Ridge National Laboratory, Department of Energy Toxicity Profiles
URL: http://rais.ornl.gov/tools/tox_profiles.html
Format: HTML
Database of toxicity profiles based on information from the EPA's Integrated Risk Information Systm (IRIS) and Health Effects Assessment Summary Tables (HEAST) and other sources. The profiles are presented in three formats with varying depth of coverage and technical level of language. They may be used to find exposure pathways, carcinogenic and noncarcinogenic human health effects, and dose response information for the available chemicals.
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Source: Risk Assessment Program, Toxicology and Risk Analysis Section, Life Sciences Division, Oak Ridge National Laboratory, Department of Energy

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2536 Office of Pollution Prevention and Toxics, Office of Prevention, Pesticides and Toxic Substances, Environmental Protection Agency (EPA) Voluntary Children's Chemical Evaluation Program (VCCEP)
URL: http://www.epa.gov/oppt/vccep/
Format: HTML
Program intended to provide public access to data on the health risks to children from exposures to certain chemicals. The website includes information on who is participating and how to participate, how to access assessments, how to prepare and submit assessments, and more.
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Source: Office of Pollution Prevention and Toxics, Office of Prevention, Pesticides and Toxic Substances, Environmental Protection Agency

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