SHEDS models are probabilistic models that estimate human chemical exposures from inhalation, skin contact, and dietary and non-dietary ingestion. Estimates are based on available data on dietary consumption, human activity, and chemical levels in food, water, air and on surfaces. The models can generate predictions of aggregate (single chemical) and cumulative (multiple chemicals) exposures over time to improve risk assessments.

CARES NG is a probabilistic model used to estimate aggregate (single chemical) and cumulative (multiple chemicals) exposure to pesticides from multiple routes and sources. Its dietary module estimates dietary exposure from pesticide residues in food or drinking water using algorithms that incorporate EPA/OPP guidance. The module can estimate exposure and cancer risk for different populations and different time frames (acute, multi-day, chronic).